Kev nce qib hauv avobenzone photostability: mechanisms thiab kev ua tau zoo

Avobenzone, txuas dav siv UVA lim hauv Sunscreens, yog qhov ua tau zoo hauv kev nqus tau UV hluav taws xob hla 310-400 nm. Txawm li cas los xij, nws cov ntxim nyiam kom phootogradation nyob rau hauv lub hnub ci tau twv nws cov kev ua tau zoo ntev thiab kev txhawj xeeb txog kev tsim cov kev phom sij. Cov kev tshawb fawb tsis ntev los no tau tsom rau kev nkag siab txog cov txheej txheem kev ua tsis zoo los txhim kho nws cov photostability tshiab.

Cov photodegradation ntawm avobzone feem ntau tshwm sim los ntawm ob-kauj ruam txheej txheem: isomerization thiab dawb tshaj plaws tsim. Raws li UV kis, avobenzone undergoes ib qho kev hloov pauv rov qab los ntawm nws cov ntawv enol mus rau ib qho tsawg kawg UV-nqus Keto Form. Qhov noomerization yog ua raws los ntawm kev tawm tsam tsis muaj zog, tsim cov radicals dawb uas txuas ntxiv ua cov molecule thiab txo nws cov peev xwm tiv thaiv. Txhawm rau txhawm rau qhov no, cov kws tshawb fawb tau tshawb xyuas peb txoj kev ua kom muaj stabilization: photosabilizers, encapsatulation, thiab synapistic lim ua ke.

Photosabilizers, xws li octocrylene thiabTinosorb® s(Basf), ua haujlwm los ntawm kev nqus cov peev txheej ntau dhau los ntawm kev zoo siab-xeev molecules, tiv thaiv omerization thiab radical tsim. Cov cabilizers no ua raws li "quenchers," vam khom avoblenzone lub neej nyob rau hauv UV kis tau. Kev tshawb fawb qhia tau tias cov qauv ua keTinosorb® sKhaws ntau dua 90% ntawm avobenzone qhov kev ua tom qab lub caij nyoog UV irradiation, muaj kev txhim kho tseem ceeb tshaj qhov tsis muaj kev ruaj ntseg.

Encapsulation technologies, xws li DSM'sParsol® Shield, Lub cev thaiv daim thaiv avoBenzone los ntawm UV teeb los ntawm emopedding nws nyob hauv ib lipid lossis polymer matrix. Qhov no tsis yog txo qis ncaj qha backodegration tab sis kuj txo qis kev sib cuam tshuam nrog lwm cov khoom muaj kev tiv thaiv pom zoo nkauj uas yuav ua rau muaj kev cuam tshuam zoo. Qhov encapsulation tau pom tias yog avoRobenlenlenlenlenlenlenpenlenlenlenlenlenlenlenlenlenlenlenlenlenlenlenlenlenlenlenlenly los ntawm 80%, thaum tseem txhim kho cov khoom ntiag tug ntawm cov khoom kawg.

Synergistic sib txuas nrog lwm cov ntxaij lim dej, xws liMexoryl® SX(L'Oréal), muab cov kev sib cais ntxiv los ntawm kev cuam tshuam kev nqus tau zoo thiab kev sib txuam ua molecular. Cov kev sib txuas ua ke no tsim kom muaj kev tiv thaiv UV ntau dua, txo qis kev ntxhov siab ntawm avoblenzone thiab txhim kho nws cov photostability.

Hauv kev xaus, kev nce qib kev tshawb fawb hauv avoBenzone ruaj khov tau txhim kho nws cov kev ua tau zoo thiab kev ntseeg tau nyob rau hauv Sunscreens. Los ntawm kev hais txog cov txheej txheem pib ntawm photoGradation, cov kws tshawb nrhiav tau tsim cov kev daws teeb meem uas tsis yog txuas ntxiv rau kev muaj kev nyab xeeb dua rau kev nyab xeeb dua, muaj kev tiv thaiv lub hnub ua haujlwm zoo dua. Cov kev hloov tshiab underscore lub luag haujlwm tseem ceeb ntawm kev tshawb fawb txog kev ua haujlwm hauv kev nce qib Sunscreen thev naus laus zis.